Major depressive disorder. Mild depressive episode , Moderate depressive episode
Conditions
Interventions
Intervention 1: average 25 patients are randomized in this group.citalopram is commenced with the initial dose of 10 mg daily, and gradually increases to 40 mg daily.this study lasts 8 weeks and we co
Treatment - Drugs
average 25 patients are randomized in this group.citalopram is commenced with the initial dose of 10 mg daily, and gradually increases to 40 mg daily.this study lasts 8 weeks and we collect patients i
average 25 patients are randomized in this group.venlafaxine starting dose is 37.5 mg daily , then gradually increases to 150 mg daily.this study lasts 8 weeks and we collect patients information incl
Sponsors
Shahid Sadughi University of Medical Science
Eligibility
Sex/Gender
All
Age
18 Years to 54 Years
Inclusion criteria
Inclusion criteria: inclusion criteria :mild to moderate major depressive disorder ; patients with primary depression or with any symptom in a month ago exclusion criteria : severe depression ;bipolarity ; anxiety disorder ; alcoholic or drug abuse ; patients with other significant medical diseases ; psychotic disorder ; pregnant women and breast feeding mothers
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of recovery of depression. Timepoint: before of study & follow up visits every a 2-weeksfor 8 weeks. Method of measurement: cheking of hamilton score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect of drugs. Timepoint: every 2 weeks for 8 weeks. Method of measurement: with history taking & blood pressure cheking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.fariba amini
Shahid Sadughi University of Medical Science
Outcome results
None listed