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A new dressing method of skin graft donor site in burn patients

A comparison between a novel combined dressing (Melolin and Flexigrid) with Fine Mesh Gauze dressing in the area of donor graft in burn patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201202278375N6
Enrollment
70
Registered
2013-02-06
Start date
2012-11-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Burning. Condition 2: Burning. Condition 3: Burning. Burns of multiple regions, at least one burn of third degree mentioned Burn of second degree, body region unspecified Burn of third degree, body region unspecified

Interventions

Treatment - Drugs
Intervention 1: Intervention group: Graft donor site dressing consists of Melolin and Flexigrid. Melolin: Manufactured by Smith and Nephew Wound Management Factory, free from adherence to the wound,
Intervention group: Graft donor site dressing consists of Melolin and Flexigrid. Melolin: Manufactured by Smith and Nephew Wound Management Factory, free from adherence to the wound, size 10 cm× 20
Control group: Graft donor site dressing is Fine Mesh Gauze. Fine mesh gauze is sterile and less adherent to the wound surface. This dressing can be dipped in a medicated solution or covered with an a

Sponsors

Vice chancellor for research, Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (1) Burn wounds which require partial thickness skin graft (2) Age 15 to 35 years (3) Burn surface area 20% to 50%. Exclusion criteria: (1) Background disease which interferes with wound healing (2) Drug history which interferes with wound healing (steroids and chemotherapy) (3) Chemical or electrical burns

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound epithelialization time. Timepoint: Wound epithelialization time will be measured daily since the start of the intervention. Method of measurement: Wound epithelialization time will be measured by inspection by one expert surgeon.;The final "cost". Timepoint: At the end of intervention. Method of measurement: The final "cost" will be measured at the end of the intervention on RLS.;Donor site "infection". Timepoint: Donor site "infection" will be measured daily since the start of intervention. Method of measurement: Donor site "infection" will be measured by wound appearance (erythema, warmth and pussy exudates), smear and culture.;"Pain" at the time of dressing change. Timepoint: At the time of dressing change. Method of measurement: "Pain" at the time of dressing change will be measured by the pain reported by patient (given a score between 0 and 10).

Secondary

MeasureTime frame
Scar. Timepoint: One month after hospital discharge. Method of measurement: Scar of graft donor site wound will be measured by Vancouver Scar Scale. The scale is based on four values: pliability, height, vascularity and pigmentation. The four categories are given a score between 0 and 4. The scale will be evaluated by a surgeon and a nurse who do not know the type of dressing one month after discharge from the hospital.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ghodrat Allah Naseh

Surgery ward, Emam Reza Educational Hospital, Birjand University of Medical Sciences

Nasehghodrat@yahoo.com+98 56 1222 2300

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026