Comparison of postoperative analgesia and side effects of ropivacine and bupivacaine by continous epidural analgesia after lower extremity orthopedic surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201202277984N4

Enrollment

120

Registered

2012-05-30

Start date

2012-02-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia after lower extremity orthopedic sugery. Fracture of bone following insertion of orthopaedic implant, joint prosthesis, or bone plate

Interventions

Intervention 1: Ropivacaine in case group. Intervention 2: Bupivacaine in control group.

Treatment - Drugs

Ropivacaine in case group

Bupivacaine in control group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18-65 years old; ASA I and II and scheduled for lower extremity orthopedic surgery. Exclusion criteria: Opioid adiction or abuse; lower extremity muscle weakness; hypersensitivity to opioids; patient refusal at any time during projetc and coagulopathy or anticoagulant therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: data were recorded at immediate before pump filling, 6, 12, 24, 36, and 48 hours later. Method of measurement: Visual Analog Scale (VAS).	—

Secondary

Measure	Time frame
Motor blockade. Timepoint: data were recorded at immediate before pump filling, 6, 12, 24, 36, and 48 hours later. Method of measurement: Bromage scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnad Imani

Tehran University of Medical ciences

farimani@tums.ac.ireditor@anesthpain.com+98 21 6650 9059

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026