Effect of paracetamol on opioid consumption after surgery

Effect of intravenous paracetamol on opioid consumption in intubated patient after major surgery in ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201202229113N1

Enrollment

Registered

2012-05-19

Start date

2011-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute post operation pain. Acute Pain

Interventions

Intervention 1: In case group we prescribe 1gr vial paracetamol in 100 cc normal salin IV infused every 6 hours in first 24 hours. Intervention 2: In control group 100cc normal salin infused every 6 h

Treatment - Drugs

Placebo

In case group we prescribe 1gr vial paracetamol in 100 cc normal salin IV infused every 6 hours in first 24 hours

In control group 100cc normal salin infused every 6 hours in first 24 hours

Eligibility

Sex/Gender

All

Age

18 Years to 69 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:between 18 to 69 years old; mechanical ventilation after surgery; Exclusion criteria:allergy;acute kidney and hepatic injury;need to resurgery;reintubation; pregnancy; smoker; drug abuse; counterindication for using opioids

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Opioid consumption after surgery. Timepoint: 0,1,2,4,6,12,24 hours after to arrived to ICU. Method of measurement: Behavioral Pain Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Soltani

Ahwaz Jondishapour University of Medical Science

fsoltan@hotmail.com+98 61 1374 3037

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026