Atherosclerotic heart disease. Atherosclerotic heart disease
Conditions
Interventions
Intervention 1: Intravenous injection of 2cc equal with 8mg of dexamethasone before surgery, following by 2cc(8mg) of dexamethasone every 8 hour for 3 day. Intervention 2: Intravenous injection of 2cc
Treatment - Drugs
Placebo
Intravenous injection of 2cc equal with 8mg of dexamethasone before surgery, following by 2cc(8mg) of dexamethasone every 8 hour for 3 day
Intravenous injection of 2cc Normal saline(placebo) before surgery, following by 2cc of normal saline every 8 hour for 3 day
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Canidateted patients for coronary baypass surgery Exclusion criteria: longer duration of cardiopulmunary bypass (more than 3 hour); age older than 80 years; EF lower than 20%; instability of hemodynamic; history of delirium; emergency operation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Delirium. Timepoint: first, 2nd, 3ed postoperative day. Method of measurement: MME questionaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intensive care unit and hospital length of stay. Timepoint: after discharge. Method of measurement: hospital documents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamid Bigdelian
Department of Cardiac surgery, Isfahan University of Medical Sciences
Outcome results
None listed