Hemodynamic Shock. Shock, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Vitamin C (Elixir, Iran)1.5 g every 6 hours in 0.9% normal saline (Qazi, Iran) was added to a volume of 50 ml through a syringe pump within 30 minutes. It is inject
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 20 years old Undergoing elective colon cancer surgery for the first time Following the postoperative shock, they are immediately admitted to the ICU
Exclusion criteria
Exclusion criteria: Sepsis before surgery Myocardial ischemia in a recent hospitalization (positive troponin test on two time) Acute kidney injury (creatinine increase 1.5 times the baseline creatinine level) Immunotherapy before surgery oxalate kidney stones G6PD enzyme deficiency History of rheumatic disease History of corticosteroid use History of rheumatic disease Morbid obesity (BMI =40) Simultaneous cancers in other organs metastatic cancer Previous colon cancer surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory factors ( IL-6, CRP, Lactate, ESR). Timepoint: At the beginning of the study and then daily for 5 days. Method of measurement: Laboratory examination of blood samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospitalization. Timepoint: From the beginning of the study until discharge or death. Method of measurement: Daily checking of the variables by the researcher.;Duration of hospitalization in the intensive care unit. Timepoint: From the beginning of the study on a daily basis until discharge or death from the intensive care unit. Method of measurement: Number of days assessed by the researcher. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Taghi Beig Mohammadi
Tehran University of Medical Sciences
Outcome results
None listed