Idiopathic sudden sensorineural hearing loss. Sudden hearing loss NOS
Conditions
Interventions
Intervention 1: Group 1) Oral prednisolone (75mg) for 10 days, and 0.6ml of intratympanic placebo at days 1,5,9,13. Intervention 2: Group 2) 0.6ml intratympanic methyl prednisolone at days 1,5,9,13 an
Treatment - Drugs
Group 1) Oral prednisolone (75mg) for 10 days, and 0.6ml of intratympanic placebo at days 1,5,9,13
Group 2) 0.6ml intratympanic methyl prednisolone at days 1,5,9,13 and oral placebo for 10 days
Group 3) oral prednisolone like group 1 and intratympanic methyl prednisolone like group 2
Sponsors
ENT Research center, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients with SSNHL referring to Amiralam hospital within the first 10 day of onset Exclusion criteria: receiving therapy in other centers; contraindication to corticosteroid such as pregnancy, diabetus mellitus, etc; previous history of SSNHL; immunocompromised subjects; fluctuating SNHL; previous history of hydropsis; history of brain pathology or temporal bone pathology; concurrent acute or chronic otitis; VDRL-positive cases; uncoopearte subjects; refering after 10 days.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hearing loss. Timepoint: Before trial, one and 4 weeks following the intervention. Method of measurement: Audiometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzad Firouzi, MD
ENT Reaserch center
Outcome results
None listed