Effect of clonidine on intraoperative consumption of propofol

The effect of pretreatment with clonidine on propofol consumption in opium abuser and non-abuser patients undergoing elective leg surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201202159026N1

Enrollment

160

Registered

2012-04-05

Start date

2012-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

general anesthesia.

Interventions

Intervention 1: In first Intervention(case) group (non addicted)& second Intervention(case) group (addicted) tab clonidine(5mic/kg)90min before operation will prescribe and then The patients will ane

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria patient informed written consent for entering study; American Society of Anesthesiologists (ASA) classification score 1 or 2 (I or II); age range of 18 to 65 years and maximum length of surgery up to 180 minutes Exclusion criteria patient disagreement; ASA class>2; SBP>140mmhg or SBP180min; age65y; cardiac arrhythmias; SaO2<90%; history of egg or propofol sensitivity; multiple trauma; addict in withdrawal phase coagulopathy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intraoperative consumption of propofol. Timepoint: During operation. Method of measurement: miligram.	—

Secondary

Measure	Time frame
Intraoperative bleeding. Timepoint: During operation. Method of measurement: Mililiter.;Recovery time. Timepoint: At the end of anesthesia. Method of measurement: Minutes.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Davood Ommi

Anesthesia departement , Shahid Beheshti University of Medical Sciences

davoodommi@yahoo.com+98 21 7756 7840

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026