Is Erythropietin effective on preventing Cisplatin induced nephropathy?

Erythropoietin effects on preventing cisplatin induced nephropathy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201202158397N3

Enrollment

Registered

2012-02-25

Start date

2012-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal failure. Renal failure

Interventions

Intervention 1: For the intervention group: In addition to their routine cis platin containing chemotherapy, which is a criteria to be included in this study, erythropoietin 100 units/kg once a day s

Prevention

For the intervention group: In addition to their routine cis platin containing chemotherapy, which is a criteria to be included in this study, erythropoietin 100 units/kg once a day subcutaneously fr

For control group: no intervention, no placebo (patients in this group will be treated with their routine chemotherapy and this treatment, which sure consists cis platin, may probably be different amo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: (to have indication for chemotherapy with cisplatine alone or together with other agents) Exclusion criteria: (to have a history of parior chemotherapy or history of prior erythropoietin consumption; to recieve another concurrent nephrotoxic agent; to have clues of renal failure)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood creatinine level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;Blood magnesium level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;24-hour urine creatinine level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;Blood Urea Nitrogen level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.	—

Measure

Time frame

Blood creatinine level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;Blood magnesium level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;24-hour urine creatinine level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.;Blood Urea Nitrogen level. Timepoint: 24 hours before the start of chemotherapy, in first day, second day, fourth day and 24 hours after the end of chemotherapy. Method of measurement: Laboratory testing.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamia Malek

Tabriz Medical University

samiamalek@ymail.com+98 41 1334 3811

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026