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Effect of intralesional Vitamin D versus intralesional Triamcinolone Acetonide on the treatment of keloids

Effect of intralesional Vitamin D versus intralesional Triamcinolone Acetonide on the treatment of keloids: a double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120215009014N609
Enrollment
24
Registered
2026-05-14
Start date
2026-05-31
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keloid. Acne keloid

Interventions

Intervention 1: Intervention group: Intralesional injection of vitamin D 300,000 units (manufactured by Caspian Pharmaceutical Co.) at a concentration of 0.2 per mL, with a maximum dose of 1 mL per le

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18 to 60 years, Keloid lesion with a maximum size of 5 cm, less than 5 years old,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, History of prior treatment within the last 3 to 4 months, Keloid lesion on the face, Active infection at the keloid lesion site.

Design outcomes

Primary

MeasureTime frame
Scar severity. Timepoint: Before the intervention and three months later. Method of measurement: Using the Vancouver Scar Scale (VSS).;Pain intensity. Timepoint: Before the intervention and three months later. Method of measurement: Using the Visual Analog Scale (VAS).

Secondary

MeasureTime frame
Local complications (burning sensation, pain, itching, inflammation). Timepoint: Three months after the intervention. Method of measurement: By taking a medical history and performing a clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyyed Mohammad Noorolahi

Hamedan University of Medical Sciences

mohammad.norolahi@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026