Effect of L-carnitine supplementation versus placebo on parameters of oxidative stress, inflammation, hematology, liver and kidney profiles in patients poisoned with aluminum phosphate

Effect of L-carnitine supplementation versus placebo on parameters of oxidative stress, inflammation, hematology, liver and kidney profiles in patients poisoned with aluminum phosphate: a single-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N606

Enrollment

Registered

2026-04-29

Start date

2026-05-12

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poisoning with aluminum phosphate. Toxic effect of phosphorus and its compounds, assault, sequela

Interventions

Intervention 1: Intervention group: Standard treatment plus intravenous L-carnitine supplementation 1 gr every 8 hours for at most 3 three days. Intervention 2: Control group: Standard treatment plus

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years, Poisoned with aluminum phosphate,

Exclusion criteria

Exclusion criteria: Swallowing disorders

Design outcomes

Primary

Measure	Time frame
Catalase. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;TAC. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;MDA. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;GSH. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ESR. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;CRP. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Hematocrit. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Hemoglobin. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Platelet. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ALT. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ASD. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Creatinine. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Urea. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Protein. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Albumin. Timepoint: Before the intervention and on second an	—

Measure

Time frame

Catalase. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;TAC. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;MDA. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;GSH. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ESR. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;CRP. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Hematocrit. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Hemoglobin. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Platelet. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ALT. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;ASD. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Creatinine. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Urea. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Protein. Timepoint: Before the intervention and on second and third days after the intervention. Method of measurement: Through spirometer.;Albumin. Timepoint: Before the intervention and on second an

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Freshteh Mehri

Hamedan University of Medical Sciences

freshteh_mehri@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026