Effect of topical minoxidil combined with topical finasteride versus topical minoxidil monotherapy in male alopecia

Effect of topical minoxidil combined with topical finasteride versus topical minoxidil monotherapy in male androgenetic alopecia: single-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N605

Enrollment

Registered

2026-04-21

Start date

2026-05-22

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenic alopecia. Androgenic alopecia

Interventions

Intervention 1: Intervention group: Topical minoxidil 5% plus topical finasteride 0.25% on alopecia location twice daily for 4 months. Intervention 2: Control group: Topical minoxidil 5% on alopecia l

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years, Male androgenetic alopecia,

Exclusion criteria

Exclusion criteria: History of treatment in the past 6 months, Cardiovascular diseases

Design outcomes

Primary

Measure	Time frame
Average of hair concentration. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;Average of hair dimeter. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;Average of hair drop. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;The rate of patient’s satisfaction. Timepoint: 4 months after the intervention. Method of measurement: Through 5-choice question in Likert scale.	—

Measure

Time frame

Average of hair concentration. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;Average of hair dimeter. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;Average of hair drop. Timepoint: Before the intervention and 4 months later. Method of measurement: Through physical examination.;The rate of patient’s satisfaction. Timepoint: 4 months after the intervention. Method of measurement: Through 5-choice question in Likert scale.

—

Secondary

Measure	Time frame
Probable treatment side effects (redness, itching, burning). Timepoint: 4 months after the intervention. Method of measurement: Through taking history.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Ashraf Abadi

Hamedan University of Medical Sciences

alireza.ashrafabadi@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026