Effect of honey syrup versus placebo on quality of life associated with gastroesophageal reflux in primigravid women

Effect of honey syrup versus placebo on quality of life associated with gastroesophageal reflux in primigravid women: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N586

Enrollment

Registered

2025-11-20

Start date

2025-12-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastro-esophageal reflux. Gastro-esophageal reflux disease

Interventions

Intervention 1: Intervention group: Routine treatment of gastroesophageal reflux plus honey syrup (with a concentration of 5 grams of healthy honey in 240 ml of water) 60 ml 4 times a day for 4 weeks.

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age 18 to 35 years, Gestational age 25 to 30 weeks, First pregnancy, Singleton, Gastroesophageal reflux, Normal body mass index,

Exclusion criteria

Exclusion criteria: Allergy to bee stings and honey, Stomach ulcer, Irritable bowel syndrome

Design outcomes

Primary

Measure	Time frame
Quality of life score. Timepoint: Before intervention and 4 weeks after. Method of measurement: Using the Gastroesophageal Reflux-Related Quality of Life Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSima Fazli

Hamedan University of Medical Sciences

mwsimafazli@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026