Effect of Bisoprolol and Metoprolol in reducing heart rate in coronary CT-angiography candidates

Effect of Bisoprolol and Metoprolol in reducing heart rate in coronary CT-angiography candidates: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N532

Enrollment

Registered

2024-10-05

Start date

2024-10-11

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CT-angiography. Coronary angioplasty status

Interventions

Intervention 1: Intervention group 1: Bisoprolol 2.5 mg tablet as a single dose and if necessary repeat the same dose one hour later. Intervention 2: Intervention group 2: Metoprolol 50 mg tablet as a

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 18 to 80 years Heart rate above 70 beats per minute

Exclusion criteria

Exclusion criteria: Systolic blood pressure lower than 100 mm Hg History of coronary bypass surgery Obstructive pulmonary disease

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.;Systolic blood pressure. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.;Diastolic blood pressure. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.	—

Measure

Time frame

Heart rate. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.;Systolic blood pressure. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.;Diastolic blood pressure. Timepoint: Before the intervention and 15, 30, 45, 60, 75, 90 and 120 during CT angiography. Method of measurement: Using the monitor device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Javad Kakavand

Hamedan University of Medical Sciences

mjkakavand1379@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026