Effect of oral Transexamic acid versus placebo on hemorrhage during spinal surgery

Effect of oral Transexamic acid versus placebo on hemorrhage during spinal surgery: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N506

Enrollment

Registered

2024-04-02

Start date

2024-04-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal surgery. Other and unspecified diseases of spinal cord

Interventions

Intervention 1: Intervention group: Routine preoperative care plus Tranexamic acid tablets orally 10 mg/kg 24 hours before surgery. Intervention 2: Control group: Routine pre-operative care plus a pla

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 18 to 70 years Candidate for spine surgery

Exclusion criteria

Exclusion criteria: Spine surgery Renal failure Taking anticoagulants

Design outcomes

Primary

Measure	Time frame
Hemoglobin level. Timepoint: Before the intervention and 24 hours later. Method of measurement: By taking a blood sample.;The volume of blood lost. Timepoint: During surgery. Method of measurement: By measuring the output volume of suction.;The amount of blood received. Timepoint: During surgery. Method of measurement: Based on the medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Soroush Shekoufandeh

Hamedan University of Medical Sciences

soroushshekoufandeh@ gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026