Effect of topical cream containing green tea and licorise extract as add-on therapy versus control group on the improvement of mild to moderate acne

Effect of topical cream containing green tea and licorise extract as add-on therapy versus control group on the improvement of mild to moderate acne: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N493

Enrollment

Registered

2023-12-12

Start date

2023-12-26

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne. Acne

Interventions

Intervention 1: Intervention group: Clindamycin topical solution 1% plus topical cream containing green tea extract and licorice twice a day for 8 weeks. Intervention 2: Control group: Clindamycin top

Eligibility

Sex/Gender

All

Age

12 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 12 to 70 years Mild to moderate acne for at least 6 months

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding Acne lesions with infection The presence of other skin diseases at the same time

Design outcomes

Primary

Measure	Time frame
Severity and extent of acne lesions. Timepoint: Before the intervention and in the fourth and eighth weeks after the intervention. Method of measurement: Based on the Global Acne Grading System (GAGS).;Quality of life of patients. Timepoint: Before the intervention and in the fourth and eighth weeks after the intervention. Method of measurement: Using Dermatology Life Quality Index (DLQI).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Aziz Malayeri

Hamedan University of Medical Sciences

zahra.azizmly@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026