Effect of Botulinum A toxin versus anticholinergic on clinical symptoms of patients with overactive bladder

Effect of Botulinum A toxin versus anticholinergic on clinical symptoms of patients with overactive bladder: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N488

Enrollment

Registered

2023-11-01

Start date

2023-11-22

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overactive bladder. Overactive bladder

Interventions

Intervention 1: Intervention group: Injection of 100 to 300 units of Botulinum A toxin in 20 to 30 points of the bladder wall with the help of a cystoscope under spinal anesthesia plus one gram of int

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age 18 to 80 years Overactive bladder

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding Neuromuscular diseases Taking anticoagulants Allergy to egg white

Design outcomes

Primary

Measure	Time frame
Severity of clinical symptoms (frequency, urgency, nocturia). Timepoint: Before the intervention and 3 months later. Method of measurement: Using International Incontinence Consultation Questionnaire (ICIQ).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges Ahmadvand

Hamedan University of Medical Sciences

nargesahmadvand72@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026