Effect of vitamin D on serum levels of CHI3L1 inflammatory factor and oxidative stress in patients with multiple sclerosis

Effect of vitamin D on serum levels of CHI3L1 inflammatory factor and oxidative stress in patients with multiple sclerosis: a before-after clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N473

Enrollment

Registered

2023-05-11

Start date

2023-05-22

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention group: Oral vitamin D3 supplement with a dose of 50,000 units once a week for 8 weeks.

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years Women with multiple sclerosis

Exclusion criteria

Exclusion criteria: Acute infection Diabetes Rheumatoid diseases Kidney dysfunction Malabsorption Autoimmune diseases

Design outcomes

Primary

Measure	Time frame
CHI3L1 serum level. Timepoint: Before the intervention and 8 weeks later. Method of measurement: Using ELISA kit.;Serum level of oxidative stress factors. Timepoint: Before the intervention and 8 weeks later. Method of measurement: Using ELISA kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSevda Asadpour

Hamedan University of Medical Sciences

sevda.asadpour@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026