Chronic pelvic pain syndrome. Pelvic and perineal pain
Conditions
Interventions
Intervention 1: Intervention group: Duloxetine tablets 30 mg daily for one week then 60 mg daily for 8 weeks. Intervention 2: Control group: Amitriptyline tablets 25 mg daily for one week then 50 mg d
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age 18 to 50 years Chronic pelvic pain syndrome for more than 6 months
Exclusion criteria
Exclusion criteria: Pregnancy or breastfeeding Suffering from endometriosis, ovarian cyst, adenomyosis, fibroid or genital malignancy Gastrointestinal diseases including irritable bowel syndrome or inflammatory bowel disease History of previous hip surgery Genitourinary infection Cognitive or mental disorders Kidney and liver dysfunction History of alcohol and substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of clinical symptoms (pain, difficulty in defecation). Timepoint: Before the intervention and one and two months after that. Method of measurement: Using the National Institutes of Health Chronic Syndrome Symptom Index (NIH-CSSI).;The rate of overall response to treatment. Timepoint: Two months after the intervention. Method of measurement: Using the Global Response Assessment (GRA) questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of side effects (nausea, vomiting). Timepoint: one and two months after intervention. Method of measurement: With history taking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRojan Ghaderzadeh
Hamedan University of Medical Sciences
Outcome results
None listed