Effect of topical ointment losartan versus placebo ointment on improvement of surgical scar

Effect of topical ointment losartan versus placebo ointment on improvement of surgical scar: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N453

Enrollment

Registered

2022-12-26

Start date

2023-01-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical scar. Scar conditions and fibrosis of skin

Interventions

Intervention 1: Intervention group: Applying losartan topical ointment on the surgical scar twice a day for 3 months. Intervention 2: Control group: Applying placebo topical ointment (eucerin) on the

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 18 to 70 years Age 18 to 70 years

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding The presence of a wound or infection at the treatment site Coagulation disorder or immune system disorder

Design outcomes

Primary

Measure	Time frame
Improvement of surgical scar. Timepoint: 6 weeks and 3 months after treatment. Method of measurement: Using Vancouver scar scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Masoud Aftabi

Hamedan University of Medical Sciences

aftabi.masoud@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026