Effect of intravenous infusion of dexmedetomidine with magnesium sulfate on control of bleeding and surgeon satisfaction during tympanoplasty surgery

Effect of intravenous infusion of dexmedetomidine with magnesium sulfate on control of bleeding and surgeon satisfaction during tympanoplasty surgery: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N427

Enrollment

Registered

2022-05-18

Start date

2022-06-05

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perforation of tympanic membrane. Perforation of tympanic membrane

Interventions

Intervention 1: Intervention group 1: Intravenous infusion of dexmedetomidine at a dose of 1 µg/kg within 15 minutes. Intervention 2: Intervention group 2: Intravenous infusion of magnesium sulfate at

Eligibility

Sex/Gender

All

Age

18 Years to 61 Years

Inclusion criteria

Inclusion criteria: Age 18 to 61 years Candidate patients for tympanoplasty

Exclusion criteria

Exclusion criteria: Pregnancy Coagulation disorders Acute or chronic renal failure Liver failure Neuromuscular diseases Cardiovascular diseases

Design outcomes

Primary

Measure	Time frame
Intraoperative bleeding volume. Timepoint: ???After surgery. Method of measurement: By measuring the volume of the suction bottle (after deducting the volume of normal saline used).;Surgeon satisfaction. Timepoint: After surgery. Method of measurement: Using 5-point Likert scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Khajavi

Hamedan University of Medical Sciences

mohamad2khajavi@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026