Effect of oral prednizolon versus intratympanic dexamethasone injection on the treatment of patients with sudden sensorineural hearing loss

Effect of oral prednizolon versus intratympanic dexamethasone injection on the treatment of patients with sudden sensorineural hearing loss: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N422

Enrollment

Registered

2022-04-18

Start date

2021-05-22

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sudden sensorineural hearing loss. Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side

Interventions

Intervention 1: Intervention group: Dexamethasone injection in the intratympanic area 0.5 ml once a week for 3 weeks. Intervention 2: Control group: Prednisolone tablets 1 mg per kg body weight up to

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 60 years; Sudden unilateral sensorineural hearing loss during the last 3 weeks;

Exclusion criteria

Exclusion criteria: Previous hearing loss; Acoustic abnormality or tumor; Acute or chronic otitis; History of ear surgery; Munir disease;

Design outcomes

Primary

Measure	Time frame
Hearing threshold. Timepoint: After the first and third months. Method of measurement: Using audiometry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saha Fakhri

Hamedan University of Medical Sciences

fakhri.soha@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026