Comparison of the effect of three drugs clomiphene, letrozole and gonadotropin on the dominant follicle and pregnancy in infertile women with polycystic ovaries

Comparison of the effect of three drugs clomiphene, letrozole and gonadotropin on the dominant follicle and pregnancy in infertile women with polycystic ovaries: a single-blind randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N417

Enrollment

384

Registered

2022-02-19

Start date

2022-04-04

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile women. Female infertility

Interventions

Intervention 1: Intervention group 1:Tablet Clomiphene (manufactured by Iran Hormone Pharmaceutical Co.) 50 mg every 12 hours for 5 days. Intervention 2: Intervention group 2:Tablet Letrozole (manufac

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 35 years; Primary or secondary infertility due to polycystic ovaries

Exclusion criteria

Exclusion criteria: Tubular problems

Design outcomes

Primary

Measure	Time frame
Dominant follicle formation. Timepoint: On day 14 of the menstrual cycle. Method of measurement: Using ultrasonography.;Development of chemical pregnancy (positive pregnancy test). Timepoint: One month after the intervention. Method of measurement: By measuring Beta-Hcg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Shahedeh Khansari

Hamedan University of Medical Sciences

dr_sh_kh@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026