Effect of antimicrobial and healing effect of hydro-alcoholic extract of Scrophularia Striata topical cream versus silver sulfadiazine topical cream and placebo in patients with second-grade burn wound

Effect of antimicrobial and healing effect of hydro-alcoholic extract of Scrophularia Striata topical cream versus silver sulfadiazine topical cream and placebo in patients with second-grade burn wound: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N408

Enrollment

Registered

2021-11-20

Start date

2021-11-22

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin burn. Burn of unspecified degree of head, face, and neck, unspecified site

Interventions

Intervention 1: Intervention group 1: Silver sulfadiazine topical cream in the first 12 hours and hydro-alcoholic extract of Scrophularia Striata topical cream in the second 12 hours on the burn locat

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 70 years; Second-grade burn wound of the skin for at least 1 square centimeter

Exclusion criteria

Exclusion criteria: Sensitivity to hydro-alcoholic extract of Scrophularia Striata; History of asthma or COPD or hey fiver; Diabetes; Using NSAID medications

Design outcomes

Primary

Measure	Time frame
Assessing the healing of burn wound. Timepoint: Daily for 10 days. Method of measurement: Via physical examination.;Assessing the possibility of infection in burn wound. Timepoint: Daily for 10 days. Method of measurement: Via physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Bagheri

Hamedan University of Medical Sciences

z.bagheri202033@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026