Effect of oral vitamin A versus control group in the prevention of retinopathy of prematurity in low birth weight neonates

Effect of oral vitamin A versus control group in the prevention of retinopathy of prematurity in low birth weight neonates: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N403

Enrollment

Registered

2021-08-21

Start date

2021-08-23

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinopathy. Retinopathy of prematurity, unspecified, unspecified eye

Interventions

Intervention 1: Intervention group: Routine care including surfactant 5 ml/kg daily and injection of Ampicillin 25 mg/kg every 12 hours and Amikacin 7.5 mg/kg every 12 hours for one week plus oral dro

Eligibility

Sex/Gender

All

Age

1 Days to 1 Months

Inclusion criteria

Inclusion criteria: Age less than a month; Neonate with birth weight less than 1500 g; Premature neonate with gestational age less than 34 weeks;

Exclusion criteria

Exclusion criteria: Congenital malformations; Heart disease or any background disease

Design outcomes

Primary

Measure	Time frame
Retinopathy. Timepoint: Before the intervention and one month later. Method of measurement: Through physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Mohamadai

Hamedan University of Medical Sciences

mayamohamadi63@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026