Effect of combined vaginal cream (including honey, olive oil, and propolis) and oral contraceptive pill versus placebo with on treatment of functional cyst of ovary

Effect of combined vaginal cream (including honey, olive oil, and propolis) and oral contraceptive pill versus placebo with on treatment of functional cyst of ovary: a randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N384

Enrollment

Registered

2021-02-16

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cyst of ovary. Follicular cyst of ovary

Interventions

Intervention 1: Intervention group 1: Combined vaginal cream (containing honey, olive, propolis) every night for 21 nights and after menstruation repeated for 21 nights. Intervention 2: Intervention g

Eligibility

Sex/Gender

Female

Age

18 Years to 49 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 49 years, Functional cyst of ovary, Cyst of ovary less than 6 cm,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Complex raptured cyst, Taking antibiotic or immunosuppressive medications to vaginal drugs in the past 2 weeks, Abnormal uterine bleedings, Liver, renal, hematologic, or central nerves system diseases or diabetes or immunodeficiency syndrome

Design outcomes

Primary

Measure	Time frame
Clinical symptoms. Timepoint: Before the intervention and 2 months later. Method of measurement: By taking history and clinical examination.;Size of the ovarian cyst. Timepoint: Before the intervention and 2 months later. Method of measurement: By ultrasonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Shayan

Hamedan University of Medical Sciences

arezoo.shayan2012@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026