Effect of combined vaginal cream (including honey, olive oil, and propolis) versus placebo with antibiotic therapy on improvement of cervicitis symptoms

Effect of combined vaginal cream (including honey, olive oil, and propolis) versus placebo with antibiotic therapy on improvement of cervicitis symptoms: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N383

Enrollment

Registered

2021-02-08

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervicitis. Gonococcal cervicitis, unspecified

Interventions

Intervention 1: Intervention group: Tablet azithromycin 1 g single-dose and tab cefixime 400 mg single-dose and tablet metronidazole 500 mg daily for 7 days patient and her husband plus combined vagin

Eligibility

Sex/Gender

Female

Age

18 Years to 44 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 44 years, Cervicitis, Married,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Taking antibiotic or immunosuppressive medications to vaginal drugs in the past 2 weeks, Abnormal uterine bleedings, Abnormal Pop-smear test in the past 12 months, Repeated vaginal shower, Alcohol consumption, Liver, renal, hematologic, or central nerves system diseases or diabetes or immunodeficiency syndrome

Design outcomes

Primary

Measure	Time frame
Symptoms of cervicitis. Timepoint: Before the intervention and 14 days later. Method of measurement: By taking history and vaginal examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Shayan

Hamedan University of Medical Sciences

arezoo.shayan2012@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026