Effect of scaling and root surface correction with and without laser on gingival crevicular fluid cytokine levels in patients with chronic periodontitis

Effect of scaling and root surface correction with and without laser on gingival crevicular fluid cytokine levels in patients with chronic periodontitis: a double-blind randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N379

Enrollment

Registered

2021-02-01

Start date

2021-02-13

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: On one side of the patient, scaling and root surface correction by a piezoelectric scaling machine with a sharp pen plus laser Cr

YSGG Er with a head of RFTP5 with 1.5 W and 30 hz with angle less than 15 degree parallel to the tooth axis for 10 minutes. Intervention 2: Control group: On the other side of the patient, scaling and

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 20 to 65 years, Chronic periodontitis, Packet depth of 4 to 7 mm without destruction of angular bone,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Generalized moderate to severe chronic periodontitis, Chronic liver or renal diseases or diabetes, Using tobacco

Design outcomes

Primary

Measure	Time frame
Gingival crevicular fluid cytokine IL-1B levels. Timepoint: Before the intervention and 3 months later. Method of measurement: Using Elisa test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahar Hemmatian

Hamedan University of Medical Sciences

sahar.hemmatian@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026