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Prophylactic effect of intravenous injection of Ondansetron versus placebo on shivering after spinal anesthesia in cesarean section

Prophylactic effect of intravenous injection of Ondansetron versus placebo on shivering after spinal anesthesia in cesarean section: a double-blind randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120215009014N362
Enrollment
72
Registered
2020-07-27
Start date
2020-03-20
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean. Single liveborn infant, delivered by cesarean

Interventions

Intervention 1: Intervention group: Intravenous Ondansetron (manufactured by Tehran Chemistry Pharmaceutical Co.) 2 ml (4 mg) single dose 0.5 hour before surgery. Intervention 2: Control group: Intrav

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 35 years, Candidate for elective cesarean,

Exclusion criteria

Exclusion criteria: Sensitivity to Ondansetron, Heart disease, Liver or kidney disease, Body temperature above 38 degree centigrade, Body temperature below 36.5 degree centigrade, Need to transfusion, Length of surgery more than 180 minutes

Design outcomes

Primary

MeasureTime frame
Observation of shivering. Timepoint: During surgery every 15 minutes and after surgery in the recovery unit every half an hour. Method of measurement: Using a standard checklist called Bedside Four Point Scale.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: After surgery in recovery unit every half an hour. Method of measurement: By taking history and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Malekfar

Hamedan University of Medical Sciences

maryamiiimalek@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026