Effect of constipation treatment versus control group on migraine headaches in children with concurrent functional constipation

Effect of constipation treatment versus control group on migraine headaches in children with concurrent functional constipation: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N361

Enrollment

100

Registered

2020-07-26

Start date

2020-03-20

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: Intervention group: Intravenous infusion of propranolol 1 mg/kg up to 80 mg/day plus oral powder Pidrolax without electrolyte 0.7 g/kg twice daily and also Bisacodyl suppository 5 mg d

Eligibility

Sex/Gender

All

Age

4 Years to 15 Years

Inclusion criteria

Inclusion criteria: Age of 4 to 15 years, Migraine headaches with concurrent functional constipation,

Exclusion criteria

Exclusion criteria: Contraindication of propranolol (asthma, liver disease, diabetes, bradycardia, heart block), Severe hypotension

Design outcomes

Primary

Measure	Time frame
Rectal impaction. Timepoint: Daily for 5 days. Method of measurement: With digital rectal exam.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Shirmohamadi

Hamedan University of Medical Sciences

mshirmoo@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026