Effect of intra-lesion injection of vitamin D3 versus cryotherapy on the treatment of plantar warts

Effect of intra-lesion injection of vitamin D3 versus cryotherapy on the treatment of plantar warts: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N358

Enrollment

192

Registered

2020-06-08

Start date

2020-05-04

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plantar wart. Plantar wart

Interventions

Intervention 1: Intervention group: Intra-lesion injection of vitamin D3 0.75 mg every 3 weeks for 3 times plus topical ointment zinc oxide 1% twice daily for 2 weeks. Intervention 2: Control group: C

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years, Plantar warts,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Immunodeficiency syndrome, Presence of wound or infection or active dermal lesion on the plantar area History of convulsion

Design outcomes

Primary

Measure	Time frame
Improvement of plantar wart. Timepoint: Every 3 weeks in the intervention group and every 2 weeks in the control group for 2 months. Method of measurement: With physical examination.	—

Secondary

Measure	Time frame
Side effects including pain, erythema, swelling, and pigmentation. Timepoint: Every 3 weeks in the intervention group and every 2 weeks in the control group for 2 months. Method of measurement: with physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shima Baniardalan

Hamedan University of Medical Sciences

shima_ba@hotmail.com6517838695

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026