Comparison of the effectiveness of the three methods: healing with dry amniotic dressing, dressing with platelet derived growth factor, and conventional surgical debridement on the improvement of diabetic foot ulcer

Comparison of the effectiveness of the three methods: healing with dry amniotic dressing, dressing with platelet derived growth factor, and conventional surgical debridement on the improvement of diabetic foot ulcer: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N352

Enrollment

123

Registered

2020-04-21

Start date

2020-05-04

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic foot ulcer. Type 2 diabetes mellitus with foot ulcer

Interventions

Intervention 1: Intervention group 1: Wound irrigation and then healing with dry amniotic dressing daily for 10 weeks. Intervention 2: Intervention group 2: Wound irrigation and then dressing with pla

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 70 years, Diabetic foot ulcer with dimension between 1 and 10 cm, Level 1 or 2 based on Vegner scale, HbA1c less than 8, Suitable tissue circulation,

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Osteomyelitis, Malnutrition, Chemotherapy or radiotherapy, Malignancy, Autoimmune diseases, Renal diseases needing dialysis, Immunosuppressive drugs

Design outcomes

Primary

Measure	Time frame
Improve diabetic foot ulcers. Timepoint: In weeks 4, 6, 8 and 10 after the intervention. Method of measurement: With clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Majid Tajik

Shahid Beheshti University of Medical Sciences

dr.m.tajik@gmail.com+98 21 8820 2521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026