Effect of honey and turmeric versus acyclovir 5% ointment on the improvement of clinical signs of labial herpes lesions: a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N349

Enrollment

Registered

2020-03-20

Start date

2020-04-05

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labial herpes. Herpesviral [herpes simplex] infections

Interventions

Intervention 1: Intervention group: Curcumin honey 5 ml (one teaspoon) 5 times daily for 7 days. Intervention 2: Control group: Topical 5% acyclovir ointment (manufactured by Tabib Tajhiz Pharmaceutic

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years, Affected with labial herpes lesions,

Exclusion criteria

Exclusion criteria: Sensitivity to honey or turmeric

Design outcomes

Primary

Measure	Time frame
Improvement of clinical signs of labial herpes lesions. Timepoint: 7 days after the intervention. Method of measurement: With clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Rezaii

Hamedan University of Medical Sciences

maliherzii@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026