Effect of botulinum toxin injection versus placebo injection in fat pad around the heart on the incidence of intra-hospital atrial fibrillation after coronary artery bypass graft (CABG)

Effect of botulinum toxin injection versus placebo injection in fat pad around the heart on the incidence of intra-hospital atrial fibrillation after coronary artery bypass graft (CABG): a songle-blind randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N338

Enrollment

Registered

2020-02-01

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial fibrillation. Unspecified atrial fibrillation

Interventions

Intervention 1: Intervention group: Injection of Botulinum Toxin Type A (manufacture by Dysport Co.) 50 U with insulin needle in fat pad around the heart single does. Intervention 2: Control group:.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 80 years, Indication of coronary artery bypass graft

Exclusion criteria

Exclusion criteria: History of previous hear surgery, Unstable angina or heart failure, Chronic atrial fibrillation, Aortic or mitral valvular disease, Liver or renal or thyroid disorder, Taking anti-arrhythmic medications

Design outcomes

Primary

Measure	Time frame
Intra-hospital atrial fibrillation after coronary artery bypass graft. Timepoint: Daily for 7 to 10 days. Method of measurement: With monitoring machine.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHosna Mohebi

Hamedan University of Medical Sciences

gp.mohebi@gmail.com+98 901 615 0379

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026