Hypoxic ischemic encephalopathy. Hypoxic ischemic encephalopathy [HIE]
Conditions
Interventions
Intervention 1: Intervention group: Routine treatment plus intravenous injection of erythropoietin 1000 U/kg/day on the first, second and third days and then every other day on the fifth, seventh, and
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Days to 28 Days
Inclusion criteria
Inclusion criteria: Newborn, Hypoxic- ischemic- encephalopathy
Exclusion criteria
Exclusion criteria: Congenital anomalies, Gestational age less than 36 weeks, Unperforated anus, Intracranial hemorrhage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to start oral nutrition. Timepoint: From the beginning of the intervention until two weeks thereafter. Method of measurement: By taking a history.;Seizure attacks. Timepoint: From the beginning of the intervention until two weeks thereafter. Method of measurement: With clinical examination.;Time of onset of consciousness. Timepoint: From the beginning of the intervention until two weeks thereafter. Method of measurement: With clinical examination.;Occurrence of death. Timepoint: From the beginning of the intervention until two weeks thereafter. Method of measurement: With clinical examination.;Duration of hospitalization. Timepoint: From the beginning of the intervention to two weeks thereafter. Method of measurement: Based on the medical document. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug complications such as induced topical hypothermia, bradycardia and subcutaneous necrosis. Timepoint: From the beginning of the intervention until two weeks later. Method of measurement: With clinical examination.;Drug complications such as thrombocytopenia. Timepoint: From the beginning of the intervention up to two weeks later. Method of measurement: By laboratory tests. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Tayebeh Ghalandari Navideh
Hamedan University of Medical Sciences
Outcome results
None listed