Antimicrobial and healing effect of hydro-alcoholic extract of Scoropholaria Striata versus topical phenytoin cream 1% on the first and second compression ulcer in patients with spinal cord injury

Antimicrobial and healing effect of hydro-alcoholic extract of Scoropholaria Striata versus topical phenytoin cream 1% on the first and second compression ulcer in patients with spinal cord injury: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N328

Enrollment

120

Registered

2019-12-28

Start date

2020-01-21

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pressure ulcer. Pressure ulcer

Interventions

Intervention 1: Intervention group 1: Topical cream phenytoin 1% (manufactured by Darupakhsh Company) on the compression ulcer every morning and then topical cream including hydro-alcoholic extract of

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 70 years, Compression ulcer grade 1 or 2, Spinal cord injury

Exclusion criteria

Exclusion criteria: Sensitivity to extract of Scoropholaria Striata, History of asthma or allergy or chronic respiratory disease, Absence of conscious, Concurrent skin lesions, Using anti-inflammatory drugs

Design outcomes

Primary

Measure	Time frame
Improvement of compression ulcer. Timepoint: 10 days after the intervention. Method of measurement: By physical examination.	—

Secondary

Measure	Time frame
Local reaction. Timepoint: 10 days after the intervention. Method of measurement: By physical examination.;Local infection. Timepoint: 10 days after the intervention. Method of measurement: By physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Bagheri

Hamedan University of Medical Sciences

z.bagheri202033@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026