Effect of topical product including Lactobacillus lysate versus placebo on the clinical symptoms in the patients with atopic dermatitis

Effect of topical product including Lactobacillus lysate versus placebo on the clinical symptoms in the patients with atopic dermatitis: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N325

Enrollment

Registered

2019-12-19

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis. Atopic dermatitis

Interventions

Intervention 1: Intervention group 1: A topical cream containing Lactobacillus rhamnosus lysate (manufactured by the laboratory of School of Pharmacy Hamadan University of Medical Sciences) twice dail

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 60 years, Atopic dermatitis for at least 6 months, Involvement of at least 20% of the body surface

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding, Involvement of inguinal or genital area, Bacterial infection, Psoriasis, Immunodeficiency disorder

Design outcomes

Primary

Measure	Time frame
Improvement of cutaneous symptoms of atopic dermatitis. Timepoint: 2 months after the intervention. Method of measurement: with clinical examination.	—

Secondary

Measure	Time frame
Sensitivity reaction due to topical cream. Timepoint: 1 and 2 months after the intervention. Method of measurement: With clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Taher Ghorbani

Hamedan University of Medical Sciences

Taher2555@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026