Effect of oral probiotic versus placebo on the improvement of the clinical symptoms in the patients with psoriasis

Effect of oral probiotic versus placebo on the improvement of the clinical symptoms in the patients with psoriasis: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N323

Enrollment

Registered

2019-12-17

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psoriasis. Psoriasis

Interventions

Intervention 1: Intervention group: Topical cream corticosteroid twice daily plus oral probiotic (manufactured by laboratory of School of Pharmacy Hamadan University of Medical Sciences) twice daily f

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 60 years, Mild to moderate psoriasis, Involvement of more than 10% of the body surface

Exclusion criteria

Exclusion criteria: Taking probiotic in the past 6 weeks, Diabetes, Immunodeficiency disorder, Taking immunosuppressive drugs

Design outcomes

Primary

Measure	Time frame
Psoriasis Area and Severity Index (PASI). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Through clinical examination.;Dermatology Life Quality Index (DLQI). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Through clinical examination.;Itching severity. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Using Visual Analog Scale (VAS).	—

Measure

Time frame

Psoriasis Area and Severity Index (PASI). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Through clinical examination.;Dermatology Life Quality Index (DLQI). Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Through clinical examination.;Itching severity. Timepoint: Before the intervention and 3 months after the intervention. Method of measurement: Using Visual Analog Scale (VAS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbarzadeh

Hamedan University of Medical Sciences

aliakbarzadehh@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026