Skip to content

Effect of CO-Q 10 supplementation spermogram parameters and sexual function in infertile men

Effect of CO-Q 10 supplementation versus placebo on spermogram parameters and sexual function in infertile men: a double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20120215009014N322
Enrollment
70
Registered
2019-12-16
Start date
2020-01-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility. Male infertility

Interventions

Intervention 1: Intervention group: Routine infertility treatment plus Q10 coenzyme capsule (CO-Q 10) (manufactured by Nature Mid Pharmaceuticals) 30 mg daily for 12 weeks. Intervention 2: Control gro

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
15 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 40 years, Man with primary infertility, Abnormality in at least one of the sperm parameters (volume, concentration, number, motility, or morphology), Body mass index less than 30,

Exclusion criteria

Exclusion criteria: Chromosomal abnormalities, Varicocele, Cryptorchidism, Chronic diseases such as diabetes, kidney disease, infectious diseases, genital tract infection, thyroid disorder, Drug or alcohol use, Taking spermatogenic drugs (methotrexate, nitrofurantoin, colchicine or chemotherapy), Taking pituitary suppressive drugs (testosterone, GnRh analogs), Taking anti-androgens (cimetidine or spironolactone), Taking alpha-blockers, antidepressants, or phenothiazide, History of testis surgery

Design outcomes

Primary

MeasureTime frame
Sperm volume. Timepoint: Before and 12 weeks after the intervention. Method of measurement: By spermogram analysis.;Sperm count. Timepoint: Before and 12 weeks after the intervention. Method of measurement: By spermogram analysis.;Sperm concentration. Timepoint: Before and 12 weeks after the intervention. Method of measurement: By spermogram analysis.;Sperm motility. Timepoint: Before and 12 weeks after the intervention. Method of measurement: By spermogram analysis.;Sperm morphology. Timepoint: Before and 12 weeks after the intervention. Method of measurement: By spermogram analysis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTaiebeh Gharakhani

Hamedan University of Medical Sciences

tabahar6@gmail.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026