Effect of N-acetyl Cysteine versus placebo as adjunct therapy on the clinical outcomes in patients with chronic non-bacterial prostatitis

Effect of N-acetyl Cysteine versus placebo as adjunct therapy on the clinical outcomes in patients with chronic non-bacterial prostatitis: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N318

Enrollment

Registered

2019-12-03

Start date

2019-12-22

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-bacterial prostatitis. Chronic prostatitis

Interventions

Intervention 1: Intervention group: Tamsulosin tablets 0.4 mg (manufactured by Reihana Pharmaceutical Company) daily plus N-acetyl Cysteine tablets 600 mg (manufactured Ave Sina Pharmaceutical Company

Eligibility

Sex/Gender

Male

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age of 20 to 40 years, Chronic non-bacterial prostatitis for at least 6 months, The severity of the clinical symptoms at least 15 based on the NIH-CPSI questionnaire

Exclusion criteria

Exclusion criteria: Taking anti-androgen medications in the past 6 months, Taking alpha-blockers or other antibiotics in the past month, Taking antioxidant or anti-inflammatory or corticosteroids medications in the past month, Genitourinary tract infection in the past 6 months, Other diseases of the genitourinary system, History of genitourinary system surgery, Chronic liver or kidney disease

Design outcomes

Primary

Measure	Time frame
The patient's clinical outcome. Timepoint: One, two, and three months after the intervention. Method of measurement: by using NIH-CPSI standard questionnaire.;The severity of pain. Timepoint: One, two, and three months after the intervention. Method of measurement: By using Visual Analog Scale (VAS).;The quality of urination. Timepoint: One, two, and three months after the intervention. Method of measurement: By taking history.	—

Measure

Time frame

The patient's clinical outcome. Timepoint: One, two, and three months after the intervention. Method of measurement: by using NIH-CPSI standard questionnaire.;The severity of pain. Timepoint: One, two, and three months after the intervention. Method of measurement: By using Visual Analog Scale (VAS).;The quality of urination. Timepoint: One, two, and three months after the intervention. Method of measurement: By taking history.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Maryam Mehrpooya

Hamedan University of Medical Sciences

m_mehrpooya2003@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026