Effect of helicobacter pylori treatment versus placebo on the prevention of the recurrence of sinonasal polyps after functional endoscopic surgery

Effect of helicobacter pylori treatment versus placebo on the prevention of the recurrence of sinonasal polyps after functional endoscopic surgery: a triple-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N309

Enrollment

Registered

2019-10-17

Start date

2018-05-22

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasal polyp. Nasal polyp

Interventions

Intervention 1: Intervention group:Sinonasal polyps surgery by functional endoscopic plus nasal Fluticasone spray one puff every 12 hours, tablet Cefixime 400 mg once daily, tablet Loratadine 10 mg ev

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years, Sinonasal polyps, Helicobacter pylori antigen positive

Exclusion criteria

Exclusion criteria: Dyspepsia or peptic ulcer or gastritis, Chronic abstractive pulmonary disease

Design outcomes

Primary

Measure	Time frame
The recurrence of sinonasal polyps. Timepoint: 1 and 3 and 6 months after the intervention. Method of measurement: By endoscopy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Aram Toolabi

Hamedan University of Medical Sciences

Toolabi_a@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026