Effect of phototherapy with and without probiotics on serum bilirubin level in term infants

Effect of phototherapy with and without probiotics on serum bilirubin level in term infants: a single-blind randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N306

Enrollment

150

Registered

2019-10-05

Start date

2019-10-23

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal jaundice. Neonatal jaundice, unspecified

Interventions

Intervention 1: Intervention group: Routine phototherapy plus probiotic oral drop (Pedilact) made by Zist-Takhmir Company 10 drops daily for 3 days. Intervention 2: Control group: Just routine phototh

Eligibility

Sex/Gender

All

Age

1 Days to 28 Days

Inclusion criteria

Inclusion criteria: Age of 1 to 28 days, Healthy infant, Birth weight above 2500 g

Exclusion criteria

Exclusion criteria: Fetal age less than 37 weeks, Immunocompatibility of blood groups, Immunocompatibility of Rh, Glucose 6 phosphate dehydrogenase deficiency, First day jaundice. Taking phenobarbital during pregnancy by the mother

Design outcomes

Primary

Measure	Time frame
Mean serum bilirubin level of infants. Timepoint: Before the intervention and 2 and 3 days after the intervention. Method of measurement: By laboratory test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoroush Taheri Talesh

Hamedan University of Medical Sciences

kopolak4@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026