Comparison of the effect of compound vaginal cream (honey, olive oil and propolis) versus Clotrimazole vaginal cream on candida vaginitis in fertile women

Comparison of the effect of compound vaginal cream (honey, olive oil and propolis) versus Clotrimazole vaginal cream on candida vaginitis in fertile women: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N290

Enrollment

116

Registered

2019-08-16

Start date

2019-08-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candida vaginitis. Acute vaginitis

Interventions

Intervention 1: Intervention group Compound vaginal cream (honey, olive oil and propolis) 60 g every night using intravaginal applicator for 7 days. Intervention 2: Control group: Clotrimazole vaginal

Eligibility

Sex/Gender

Female

Age

18 Years to 44 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 44 years Married fertile women Candida vaginitis

Exclusion criteria

Exclusion criteria: Current using antifungal, antibiotic, immunosuppressive drugs or OCP Unusual uterine bleeding Recurrent Volvo vaginitis Pregnancy Breastfeeding Using alcohol

Design outcomes

Primary

Measure	Time frame
Assessing the vaginal lesions. Timepoint: Before the intervention and one week after the intervention. Method of measurement: By physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArezoo Shayan

Hamedan University of Medical Sciences

Arezoo.shayan2012@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026