Effect of Helicobacter pylori eradication versus no eradication on disease period and treatment response in children with nephrotic syndrome

Effect of Helicobacter pylori eradication versus no eradication on disease period and treatment response in children with nephrotic syndrome: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N268

Enrollment

Registered

2019-04-11

Start date

2019-03-11

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephrotic syndrome. Nephrotic syndrome

Interventions

Intervention 1: Intervention group: Corticosteroid tablet 60 mg/m2 daily for 2 years plus four-drug treatment for 2 weeks with omeprazole capsule 1 mg/kg daily and metronidazole tablet 20 mg/kg daily

Eligibility

Sex/Gender

All

Age

2 Years to 14 Years

Inclusion criteria

Inclusion criteria: Age of 2 to 14 years; Nephrotic syndrome; Helicobacter pylori positive

Exclusion criteria

Exclusion criteria: Glomerulonephritis; Renal failure; High blood pressure; Using antibiotic or antacid in the past month

Design outcomes

Primary

Measure	Time frame
Assessing the proteinuria. Timepoint: At the end of the first, second and third months. Method of measurement: Through the laboratory test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Danyal Isapour

Hamedan University of Medical Sciences

danyal-Isapour@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026