Effect of using metformin on the incidence of gestational diabetes and preeclampsia in pregnant women with polycystic ovary

Effect of using metformin versus not using on the incidence of gestational diabetes and preeclampsia in pregnant women with polycystic ovary: A randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N252

Enrollment

170

Registered

2018-11-24

Start date

2018-12-06

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Gestational diabetes. Condition 2: Pre-eclampsia. Gestational diabetes mellitus in pregnancy Pre-eclampsia

Interventions

Intervention 1: Intervention group: Routine care during pregnancy and tablet metformin 1000 to 2000 mg (1 or 2 tablets) daily until end of pregnancy. Intervention 2: Control group: Just routine care d

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 40 years; Pregnant; Polycystic ovary

Exclusion criteria

Exclusion criteria: A history of repeated abortion; Uterine abnormality; A history of chronic disease such as lupus and renal failure

Design outcomes

Primary

Measure	Time frame
Assessing the gestational diabetes. Timepoint: Every 3 months until end of pregnancy. Method of measurement: Through laboratory diagnostic test measuring blood glucose.;Assessing the preeclampsia. Timepoint: Every 2 weeks until end of pregnancy. Method of measurement: By physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Elham Ghasemi

Hamedan University of Medical Sciences

eghasemi1395@yahoo.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026