Effect of Gabapentin and Pregabalin premedication versus placebo on pain after septoplasty with and without turbinoplasty

Effect of Gabapentin and Pregabalin premedication versus placebo on pain after septoplasty with and without turbinoplasty: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N248

Enrollment

Registered

2018-11-09

Start date

2017-04-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deviated nasal septum. Deviated nasal septum

Interventions

Intervention 1: Intervention group 1: Gabapentin capsule 600 mg (2 capsules 300 mg) single dose 2 hours before surgery. Intervention 2: Intervention group 2: Pregabalin capsule 300 mg (2 capsules 150

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years; Candidate for septoplasty

Exclusion criteria

Exclusion criteria: Concurrent nasal fracture; Need for sinus endoscopy; Addiction

Design outcomes

Primary

Measure	Time frame
Measuring pain. Timepoint: ??At 2, 6 and 16 hours after surgery. Method of measurement: Using visual analog scale (VAS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Amin Karimian

Hamedan University of Medical Sciences

hqoraishi@gmail.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026