Effect of levetiracetam and sodium valproate versus sodium valproate alone on epileptiform discharges in electroencephalogram in interictal phase in children with epilepsy

Effect of levetiracetam and sodium valproate versus sodium valproate alone on epileptiform discharges in electroencephalogram in interictal phase in children with epilepsy: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N246

Enrollment

Registered

2018-10-22

Start date

2018-06-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy. Epilepsy and recurrent seizures

Interventions

Intervention 1: Intervention group: Tablet levetiracetam 50 mg/kg daily for 60 year and tablet sodium valproate 20 to 30 mg/kg daily for one year. Intervention 2: Control group: Tablet sodium valproat

Eligibility

Sex/Gender

All

Age

2 Years to 15 Years

Inclusion criteria

Inclusion criteria: Age of 2 to 15 years; Idiopathic or cryptogenic epilepsy

Exclusion criteria

Exclusion criteria: Severe seizure syndrome; Frequent convulsions

Design outcomes

Primary

Measure	Time frame
Assessing the epileptiform discharges in interictal phase. Timepoint: Every 3 months for one year. Method of measurement: Using electroencephalogram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Hussein Ebrahimi

Hamedan University of Medical Sciences

dr.mhe46@gmail.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026