Comparison of the effect of local and intravenous Tranexamic Acid and Phenylephrine Shrink on control of bleeding in patients with epistaxis

Comparison of the effect of local and intravenous Tranexamic Acid and Phenylephrine Shrink on control of bleeding in patients with epistaxis: a double-blind randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N244

Enrollment

Registered

2018-10-20

Start date

2018-10-23

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epistaxis. Epistaxis

Interventions

Intervention 1: Intervention group 1: Injection of Tranexamic Acid 1 gr single dose. Intervention 2: Intervention group 2: Use of local tampon stained with Tranexamic Acid 500 mg once. Intervention 3:

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 70 years; Epistaxis

Exclusion criteria

Exclusion criteria: Hypertension; Contraindication of Phenylephrine; A history of coagulopathy; A history of nasal surgery

Design outcomes

Primary

Measure	Time frame
Assessing the bleeding rate. Timepoint: 5 and 10 minutes after intervention. Method of measurement: By physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sadegh Chaeichi

Hamedan University of Medical Sciences

sadeghchaeichi@gmail.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026