Effect of infertility treatment with and without addition of autologous platelet-rich plasma in embryo transfer in patients candidate for intra cytoplasmic sperm injection

Effect of infertility treatment with and without addition of autologous platelet-rich plasma in embryo transfer in patients candidate for intra cytoplasmic sperm injection: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N230

Enrollment

Registered

2018-08-24

Start date

2022-09-23

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility. Female infertility

Interventions

Intervention 1: Intervention group: Routine infertility treatment plus injection of autologous platelet-rich plasma 20% once. Intervention 2: Control group: Just routine infertility treatment.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age of 20 to 40 years; Candidate for embryo transfer; Having at least two embryos of good quality to transfer; Having a healthy uterus cavity

Exclusion criteria

Exclusion criteria: Patients in need of sperm donation; Patients in need of ovum donation; Previous history of embryo transfer; Endocrine diseases such as hyperthyroidism, hypothyroidism, hyperprolactinemia, diabetes

Design outcomes

Primary

Measure	Time frame
Chemical pregnancy. Timepoint: 14 days after intervention. Method of measurement: Through laboratory test.;Clinical pregnancy. Timepoint: 21 days after intervention. Method of measurement: By sonography.;Seeing fetal heart. Timepoint: 28 days after intervention. Method of measurement: By sonography.	—

Secondary

Measure	Time frame
Abortion. Timepoint: 28 days after intervention. Method of measurement: Through history taking.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Fahimeh Salari Shahre Babaki

Hamedan University of Medical Sciences

fahimesalarii67@gmail.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026