Effect of fluoride varnish, mouthwash, and Diode laser versus no intervention on enamel white spot lesions in orthodontic patients

Effect of fluoride varnish, mouthwash, and Diode laser versus no intervention on enamel white spot lesions in orthodontic patients: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20120215009014N219

Enrollment

Registered

2018-05-05

Start date

2018-03-16

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic patients. Encounter for fitting and adjustment of orthodontic device

Interventions

Intervention 1: Intervention group 1: Covering tooth surface with fluoride varnish for 4 min and then Diode laser irradiation 980 nm, 1 w, 600 µm, once. Intervention 2: Intervention group 2: Covering

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 65 years Having bracket Enamel white spot lesions

Exclusion criteria

Exclusion criteria: Wide dental caries Inappropriate oral hygiene Systemic diseases Smoking A history of chemotherapy or radiotherapy A history of fluoride therapy in the last 3 months Pregnancy

Design outcomes

Primary

Measure	Time frame
Assessing the enamel white spot lesions. Timepoint: Before intervention and then every month for three months. Method of measurement: Through physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Sara Ebrahimi

Hamedan University of Medical Sciences

sara_ebrahimi64@yahoo.com+98 81 3838 0572

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026